Theoretical and experimental approaches to understand morphogen gradients
نویسندگان
چکیده
منابع مشابه
Theoretical and experimental approaches to understand morphogen gradients
Morphogen gradients, which specify different fates for cells in a direct concentration-dependent manner, are a highly influential framework in which pattern formation processes in developmental biology can be characterized. A common analysis approach is combining experimental and theoretical strategies, thereby fostering relevant data on the dynamics and transduction of gradients. The mechanism...
متن کاملMorphogen transport: theoretical and experimental controversies.
UNLABELLED According to morphogen gradient theory, extracellular ligands produced from a localized source convey positional information to receiving cells by signaling in a concentration-dependent manner. How do morphogens create concentration gradients to establish positional information in developing tissues? Surprisingly, the answer to this central question remains largely unknown. During de...
متن کاملMorphogen Gradients: Expand and Repress
An expansion-repression mechanism by which morphogen gradients can adjust to size and growth had been postulated as a model. Now, its molecular nature has been uncovered.
متن کاملExperimental and Theoretical Approaches to Conscious Processing
Recent experimental studies and theoretical models have begun to address the challenge of establishing a causal link between subjective conscious experience and measurable neuronal activity. The present review focuses on the well-delimited issue of how an external or internal piece of information goes beyond nonconscious processing and gains access to conscious processing, a transition characte...
متن کاملScaling of morphogen gradients.
Individuals of the same or closely related species can vary substantially in size. Still, the proportions within and between tissues are precisely kept. This adaptation of pattern with size termed scaling, is receiving a growing attention. We review experimental evidence for scaling, and describe theoretical models for mechanisms that scale morphogen gradients. We particularly note the Expansio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Systems Biology
سال: 2008
ISSN: 1744-4292,1744-4292
DOI: 10.1038/msb.2008.14